NTEN published my somewhat snarky predictions for nonprofits' use of fundraising technologies in 2012. My overall predictions are that most things will be pretty much the same as last year (and 2010 and 2009, etc.): many nonprofits will struggle with out-of-date systems. No surprise -- many will also lack the funding to replace them. But others will fail to see that technology, and people who know how to support and use technology, are necessary investments.
On the other hand, many organizations (and this by no applies just to nonprofits) will throw money and time at trendy projects without thinking about whether they're the right tools, with the right strategy, investment, support, or marketing behind them. By all means, try new things. But do it smartly. Do your homework, test, learn from others, learn from your own failures, and get better at it over time. And don't neglect what's already working for you.